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Dr. Daniel Soffer, MD

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Preventive cardiologist, Cardiologist, Lipidologist · Physician (MD)

Philadelphia, PA

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Preventive cardiologist and clinical lipidologist at Penn Medicine, Director of Education for Preventive Cardiology and Clinical Lipidology, past president of the National Lipid Association, who treats familial and complex lipid disorders with guideline-based therapy.

About Dr. Daniel Soffer, MD

Updated Sep 20, 2026 · next review Dec 19, 2026

Dr. Daniel E. Soffer is an internist and clinical lipidologist at Penn Medicine in Philadelphia and Radnor, Pennsylvania. He sees patients age 18 and up at the Penn Heart and Vascular Center, and his practice is listed under Cardiology and Medical Genetics (https://www.pennmedicine.org/providers/daniel-soffer). He went to medical school at the University of Pennsylvania (graduating in 1994) and did his residency in the University of Pennsylvania Health System (https://www.pennmedicine.org/providers/daniel-soffer, https://npiprofile.com/npi/1205863198).

His focus is cholesterol and prevention of heart disease. He is a Diplomate of the American Board of Clinical Lipidology and of the American Board of Internal Medicine, and a Fellow of the National Lipid Association (https://www.pri-med.com/globals/faculty/s/soffer-daniel, https://theproof.com/why-you-should-test-apob-dan-soffer-md/). He served as President of the National Lipid Association from June 2023 to June 2024 and is now listed as a Past President (https://www.pennmedicine.org/providers/daniel-soffer, https://www.lipid.org/meetings/sessions/faculty).

He teaches as well as treats patients. He is an Associate Professor of Clinical Medicine at the Perelman School of Medicine, Director of Education for Preventive Cardiology and Clinical Lipidology at Penn, co-Director of the Preventive Cardiology Fellowship Program at Pennsylvania Hospital, and co-Director of Penn's Foundations of Culinary Medicine course (https://theproof.com/the-case-for-treating-cholesterol-before-plaque-appears-dr-thomas-dayspring-and-dr-dan-soffer/). His Penn team offers nutrition and genetic counseling, advanced blood and imaging tests, apheresis when appropriate, and access to clinical trials (https://www.pennmedicine.org/providers/daniel-soffer).

He has co-authored national documents on cholesterol testing and treatment, including a 2024 focused update to the National Lipid Association statement on lipoprotein(a) and an expert consensus on apolipoprotein B (https://www.sciencedirect.com/science/article/pii/S1933287424000333, https://www.lipidjournal.com/article/S1933-2874(24)00240-X/abstract). Public CMS Open Payments records for 2021-2025 show $30,578.60 across 35 records from drug and device companies. Payments like these are common and legal, and are disclosed by law.

Board certifications
He is a Diplomate of the American Board of Clinical Lipidology and of the American Board of Internal Medicine, and a Fellow of the National Lipid Association. pri-med.com
National Lipid Association president
He served as President of the National Lipid Association from June 2023 to June 2024 and is listed by the society as a Past President. lipid.org
Penn Medicine practice
He practices at the Penn Heart and Vascular Center and in Radnor, listed under Cardiology and Medical Genetics and accepting new patients age 18 and up. pennmedicine.org
Training at Penn
He graduated from the Perelman School of Medicine at the University of Pennsylvania in 1994 and completed residency in the University of Pennsylvania Health System. npiprofile.com
Teaching roles
He is Director of Education for Preventive Cardiology and Clinical Lipidology at Penn, co-Director of the Preventive Cardiology Fellowship at Pennsylvania Hospital, and co-Director of Penn's Foundations of Culinary Medicine course. theproof.com
Lipoprotein(a) statement co-author
He was a co-author on the 2024 focused update to the National Lipid Association scientific statement on the use of lipoprotein(a) in clinical practice, credited with writing review and editing. sciencedirect.com
Apolipoprotein B consensus
He is an author on the National Lipid Association expert clinical consensus on the role of apolipoprotein B in managing cardiovascular risk in adults. lipidjournal.com
Regional lipid leadership
He serves on the Board of Directors of the Northeast Chapter of the National Lipid Association and on the steering committee of the Philadelphia Lipid and Atherosclerosis Club. pri-med.com
Services offered by his team
His Penn team provides nutrition and genetic counseling, advanced biochemical and imaging testing, apheresis when appropriate, and access to clinical trials. pennmedicine.org
Public education talks
He appears as a guest speaker on lipid topics, including a program on clinical challenges in high triglycerides with Dr. James Underberg. youtube.com

Worth knowing

  • CMS Open Payments records for 2021-2025 list $30,578.60 in industry payments across 35 records. The largest reported payers were Regeneron Pharmaceuticals ($8,336.65), Novartis Pharmaceuticals ($6,149.34 and $5,469 under two listings), Amryt Pharma Holdings ($4,230), and HeartFlow ($2,212.94). Such payments are common and legal, and several of these companies make cholesterol-related products. openpaymentsdata.cms.gov
  • Some podcast show notes place the X handle @Drlipid near his name, but that account belongs to a co-guest, Dr. Thomas Dayspring, not to Dr. Soffer. theproof.com

Industry payments (CMS Open Payments)

Open the CMS record

Federal law requires drug and device companies to report what they pay clinicians: meals, travel, speaking, consulting, and research. Payments are common and legal; the point is that you can see them.

2021 to 2025

$30,579

35 payments

2021$3,285
2022$5,229
2023$9,934
2024$10,665
2025$1,465

Top payers

  • Regeneron Pharmaceuticals, Inc.$8,337
  • Novartis Pharmaceuticals Corporation$6,149
  • NOVARTIS PHARMACEUTICALS CORPORATION$5,469
  • Amryt Pharma Holdings Ltd$4,230
  • HEARTFLOW, INC.$2,213

Payment types

  • Consulting Fee$27,870
  • Food and Beverage$1,759
  • Honoraria$950

A word of caution about these numbers

A payment does not mean your doctor is compromised or acting unethically. Most of these entries are drug samples left for patients, or lunch brought in for the office staff, and the amounts are usually small. Research funding and speaking at medical meetings are also normal parts of a clinical career.

As a rough guide, a total under $15,000 a year is usually not a concern. Much larger sums, especially from one company whose product your doctor recommends to you, are worth asking about. You are allowed to ask.

Sources: pennmedicine.org · x.com · linkedin.com · youtube.com · theproof.com · theproof.com · npiprofile.com · pri-med.com. Something wrong or out of date? Tell us and we will correct it.

Summary prepared with AI assistance from the public sources linked above, reviewed every three months. It is not a review, a rating, or an endorsement.

Practice location

  • Penn Heart and Vascular Center

    3400 Civic Center Blvd, Perelman Center for Advanced Medicine, East Pavilion, 2nd Floor

    Philadelphia, PA 19104

    (215) 615-4949

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